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Same-Class Alternative (Future) Ribupatide For patients who need a dual GLP-1/GIP agonist but cannot access or tolerate tirzepatide, ribupatide could provide an alternative within the same drug class once approved

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Therefore, these results indicate that the inhibition of NF-B pathway contributes to promote SGNs survived from peroxynitrite injury, and that GPX1 protects SGNs against peroxynitrite-induced damage, at least in part, via blocking the NF-B pathway activation

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