Mistake 1: Taking it with a heavy meal
I was scared that it would hurt and I needed over an hour alone in the bathroom to pluck-up the courage
But in the absence of that, to just say, Its the wild wild west
Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1 inhibition
The two signals overlap in time, which is the condition under which their synergy can express itself
Supplementary Information References Summary Keywords brain aging, aging metabolism, brain energy metabolism, neurometabolic coupling, neuro-glia-vascular system, metabolism model, aging brain model, differential equations model Citation Shichkova P, Coggan JS, Kanari L, Boci E, Favreau C, Antonel SM, Keller D and Markram H (2025) Breakdown and repair of metabolism in the aging brain