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I add this meaning since the study below and the following audits, had the very opposite effect on preventing illness in B12 deficient patients.) This report states

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Finally, in a meta-analysis of randomized trials on the use of vitamin B supplements for homocysteine reduction, folate supplementation had no significant effect on the 5-year incidence of CHD

they are complementary, not interchangeable

After reviewing literature and conducting a two-round Delphi survey with 42 experts, a consensus emerged that emphasizes prioritizing clinical symptoms in diagnosis, with serum B12 as a screening marker supported by methylmalonic acid or homocysteine levels for additional confirmation

This indicates that B12 has very close relation with folate