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Chromatin immunoprecipitation (ChIP) demonstrated increased occupancy of H2AX and decreased occupancy of all three acetylation marks at DSBs in both IDH1 inhibitor-treated and TMLHE-knockdown cells (Fig

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The pathways do not overlap

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In addition, some experimental and clinical data suggested that early intravenous supplementation with L-carnitine could improve survival in severe valproic acid -induced hepatotoxicity [5]