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The trial did not achieve its primary endpoint of demonstrating non-inferiority to tirzepatide

That said, potential risks exist: You might experience redness, pain, or swelling at injection sites

The retention concentrates in ankles, wrists, and face due to IGF-1 receptor activation in renal tubules increasing sodium reabsorption

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Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release

Additionally, GPX activity decreased noticeably after 6 h, 1 and 3 days