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A vitamin B12 shortage can cause a variety of health issues, ranging from exhaustion to permanent neurological abnormalities

References Agnoli C, Baroni L, Bertini I et al

This complete absence of tolerability-driven discontinuations represents a remarkable safety finding and indicates that even when mild side effects occurred, they were sufficiently manageable that participants chose to continue treatment

In landmark mouse studies, oral 5-amino-1MQ produced robust reductions in adipocyte size, body fat and inflammatory adipokines while leaving food intake unchanged pointing to a fundamentally novel metabolic-rejuvenation mechanism that operates entirely on the methylationNAD axis

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