how does glp-1 affect the brain Glucagon-like peptide-1 medicines in neurological and psychiatric disorders: Cell Reports Medicine Schematic representation of GLP-1 biological

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Evidence from metabolic organs suggests a potential biphasic behavior, early contact enrichment and heightened flux followed by late-stage decoupling (Theurey and Rieusset, 2017), raising the possibility that GLP-1R agonists may exert qualitatively different effects depending on whether the limiting factor is excessive Ca 2+ transfer versus structural collapse of tethering and scaffolding networks

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