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Factors such as your baseline metabolic rate, genetic makeup, underlying insulin resistance, hormonal imbalances, and starting weight all influence how strongly and quickly you respond to GLP-1 medications

Plus, side effects like vomiting and diarrhea can contribute to dehydration

If Benadryl speeds up or slows down the breakdown of Semaglutide in the liver, it could affect how long Semaglutide stays active in your body

Most patients report decreased hunger between meals and feeling satisfied with smaller portions

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This gradual increase in dosage is designed to keep side effects manageable as your body gets used to the medication