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Biochem Biophys Res Commun 495:4652 Lukey MJ, Greene KS, Erickson JW, Wilson KF, Cerione RA (2016) The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy
In case there isnt enough glutathione present in cells during the process of sperm formation, the free radicals cant be blocked from damaging the membrane, as well as the spermatozoa shielded by it, which has been proven in studies performed on infertile men
Tapping new chemically synthesized drugs or naturally isolated drugs by interfering with the ferroptosis mechanism contributes to tumor drug development and synergistic therapeutic strategies (49)
doi: 10.1084/jem.20051511 232 SmythMJTengMWLSwannJKyparissoudisKGodfreyDIHayakawaY
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