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Researchers measure lesion area via endoscopic or gross pathology examination, alongside molecular markers of inflammation such as TNF-alpha, IL-1 beta, and COX-2 expression in gastric tissue samples

The picture is one of systems-level pharmacology rather than single-target agonism

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For a supplement containing 100 IU of RRR-alpha tocopherol: 100 IU X 0.67 = 67 mg alpha-tocopherol Example 2

The 800 mg/kg SPAE group (Figure 4D) demonstrated marked histological restoration