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Diabetes also increases the morbidity and mortality of these patients, by contributing to higher rates of infections, cardiovascular events, and malignancy
Both are released in response to eating nutrientsspecifically amino acids, glucose, dietary fiber, and fatty acids in food
Conclusion The evidence supports a nuanced conclusion regarding GLP-1 agonists for obesity in non-diabetic patients: they represent a significant therapeutic advance with game-changing potential currently limited by practical implementation challenges
These medications appear to influence brain reward pathways, potentially offering a new approach to addressing substance use disorders
Serious side effects are rare but may require immediate medical attention
It has been observed that short acting GLP-1 receptor agonists exert their primary hypoglycemic effect by lowering postprandial glucose due to their inhibitory effect on gastric emptying
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