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Factors such as UV exposure, pollution, hormonal changes, stress, and ageing can stimulate excess melanin production, leading to uneven tone, dark spots, and dull-looking skin

Cell Death Disco

Tong, K.I., et al., Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response

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Nature 426 , 3944 (2003)

Flavonoids further enhance renal health by inhibiting inflammation through NF-B pathway, reducing proinflammatory cytokines (IL-6, IL-1, TNF), and decreasing leukocyte infiltration