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Prescribers and providers must understand that prescribing unlicensed medicines like glutathione outside of a genuine clinical diagnosis and therapeutic need is both dangerous and illegal

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Iacucci, M

2017;140:17789.e9

Astrocytes secrete matrix metalloproteinase-3 (MMP-3), disrupting neuron-glial metabolic coupling and reducing neurotrophic factors (e.g., glial-cell-line-derived neurotrophic factor (GDNF)), further suppressing autophagy [170]

This dynamic regulation is crucial for maintaining energy balance and responding to changes in dietary intake, physical activity, and environmental conditions