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Without resistance training and adequate protein, this can slow metabolism and impair physical function

Neuroscience 2015, 305: 225237

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doi: 10.7326/M22-3078 7 MarsoSPDanielsGHBrown-FrandsenKKristensenPMannJFNauckMAet al

Concomitant use of semaglutide with insulin or insulin secretagogues may result in hypoglycemia, and a dose reduction in the concomitant medication may be necessary