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In the kidney, elevated ROS levels contribute to pathological changes such as glomerulosclerosis, tubular atrophy, and interstitial fibrosis, primarily through the activation of pro-inflammatory and pro-fibrotic signaling pathways, such as NF-B and TGF- (71)

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This is where the concept of "Genomic Safeguarding" shines

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It uses the Na + -driven LC / organic cation transporter-2 (OCTN-2) for its transport into the oocytes [74]

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