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These medications were initially developed to help lower blood sugar in people with type-2 diabetes

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Stacking Protocols Critical: Community sources warn against combining multiple senolytics simultaneously and describe allowing adequate recovery between senolytic courses (minimum 4-6 weeks), running each compound individually first, and monitoring bloodwork (CBC, CMP, inflammatory markers) between courses

This combination of increased usage and expanded state coverage has increased Medicaid spending on GLP-1s for obesity to more than $500 million in October 2024 alone, with total expenditures reaching $3.5 billion over the past 12 months

This suggests a potential synergistic action between GHK-Cu and HA, specifically in enhancing collagen IV levels

Machado, M