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Retinoids and acids work primarily through exfoliation

Western Blotting Purified protein samples were suspended in 1 sodium dodecyl sulfate (SDS) loading buffer (250 mM Tris-HCl pH 6.8, 40% glycerol (v/v), 10% SDS (w/v) (SB0485, Biobasic), 0.05% bromophenol blue (w/v) (0449-25G, Amresco), 5% 2-mercaptoethanol (M6250-100ML, Sigma)) and heated for 5 min at 95C

Concurrently, the nanoreactors also activate the systemic immune system in mice, preventing tumor metastasis and recurrence

In addition to improving drug delivery, NPs can be designed to promote immune self-tolerance and confer added functionality depending on surface coatings and material properties [9, 10]

doi: 10.1046/j.1432-1033.2003.03906.x 115 SzymaskaR.lesakI.OrzechowskaA.KrukJ

Pierre Hofstee P, Bartho LA, McKeating DR, Radenkovic F, McEnroe G, Fisher JJ, Holland OJ, Vanderlelie JJ, Anthony V, Perkins AV, JSM C