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doi: 10.1038/s42003-023-05477-8 115 EberhardYMcDermottSPWangXGrondaMVenugopalAWoodTEet al

Yucca Health May Align Well With People Who: Have tried diet and exercise without sustained success: If you've made genuine efforts to lose weight through calorie reduction and increased activity but haven't achieved lasting results, GLP-1 medications combined with lifestyle changes may provide additional support by addressing the biological factors that make sustained weight loss difficult

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Phase 2 data published in November 2025 and presented at ADA 2026 showed mean weight loss up to 20% at 52 weeks with once-monthly dosing and no plateau