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Our data suggests a couple of key reasons

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But in Type 1 diabetes: They do not replace insulin They may promote ketogenesis Insulin dose reductions can trigger euglycemic DKA Appetite suppression and GI effects may worsen metabolic instability Type 1 diabetes management requires maintaining enough insulin not only for glucose control, but also to suppress ketone production

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The gut microbiome encompasses a complete array of microorganisms including bacteria, viruses, fungi, and protozoa (90)