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Another study published in JAMA Ophthalmology in February of 2025 analyzed data from 37.1 million adults with type 2 diabetes across 14 databases in the U.S

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Side Effects, Safety, and Treatment Considerations Semaglutide and retatrutide share the same side effects in terms of the most commonly reported adverse events: nausea, constipation, and gastrointestinal discomfort, particularly during dose escalation

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