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We also found a positive effect of AOX supplementation on sperm morphology after the exclusion of studies carried out in patients with varicocele or treated with varicocele repair and AOX or placebo/no treatment [29, 31, 32, 50, 55], including a total of 1,413 infertile men (weighted MD 1.34% [95% CI: 0.13, 2.56]

The avidity of these antibodies remains unclear and it is possible that they represent non-specifically auto-reactive antibodies generated as part of a polyclonal humoral response to a viral or other infection

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The authors speculated that variations in participant characteristics, such as age or gender, might account for discrepancies between their findings and those of previous studies

doi: 10.1016/j.nurt.2010.05.003 139 OnoreCCareagaMAshwoodP

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