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GMP standartlarnda retim, hammaddeden son kullancya kadar olan srete hammadde , ileme, rn gelitirme, retim, paketleme, depolama, datm aamalarnda kesintisiz uygulanmas gereken bir kalite kontrol unsurudur

The traditional habit of chewing raw rather than dry areca-nut with lime appears to be an important causative factor in addition of tobacco 2,3

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Current therapies are largely symptomatic, relying primarily on dopaminergic replacement therapy, with levodopa still representing the most effective option for motor symptom control [5]