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Berberine might be a good option for folks dealing with blood sugar swings, prediabetes, or polycystic ovary syndrome (PCOS), a hormonal condition associated with insulin resistance, says Dr

Managing insulin resistance through lifestyle changes and medications can be an important aspect of PCOS treatment

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But the negative reviews emphasize dependence concerns and difficulty transitioning off the medication

Average 15-20% body weight loss Clinical trials show participants lost 15.2% of body weight over 68 weeks with GLP-1 2.4mg weekly

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