Most manufacturers recommend using opened vials within 28 days when stored in a refrigerator at 2C to 8C (36F to 46F)
Prices typically range from $20 to $60 per injection or more
The sublingual route bypasses first-pass hepatic metabolism entirely, delivering the compound directly into the bloodstream via the sublingual vein
Blood clots can stop the blood flowing to different body organs, leading ultimately to widespread organ damage resulting in devastating consequences, as strokes and possibly heart attacks
A systematic review found no clinical safety data beyond a very small case series, emphasizing that the safety profile for chronic use in humans remains uncharacterized
Recent analysis shows that the antibodies induced in the small population of SARS-CoV-1-exposed individuals who were subsequently exposed to SARS-CoV-2 appear to be particularly broadly cross-reactive, suggesting that exposure to related coronavirus species can select for cross-reactive antibodies [81]