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The primary outcome measure is time to first major cardiovascular event over five years of follow-up

FDA approval of Foundayo, the only approved GLP-1 pill that can be taken any time of day, without food and water restrictions. An oral GLP-1 dramatically expands the addressable obesity market beyond injectables

GLPs can reduce appetite so much that patients unintentionally skip meals or eat very small portions without enough variety

And so initial evidence around the new obesity drugs represents good news, indicating that motivation to exercise and levels of physical activity both increase among those taking these drugs

Keep it separated from household medications and clearly marked to prevent accidental use by family members

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