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There are typically multiple underlying components that need to be identified and successfully treated
PubMed Central, Laciak, Adrian R., et al
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In vitro models to study confinement-induced responses include micropatterned lines [151], 2D micropatterned substrates [85], uni-axial compression [152], polydimethylsiloxane [153,154,155,156]- or polyacrylamide [90]-based microchannel devices, microniches [157, 158], and natural hydrogels [148, 159]
Beyond its effects on metabolic health, intermittent fasting (IF) has also garnered considerable attention for its regulation of the neuroimmune microenvironment