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Tirzepatide targets GIP and GLP-1

Other medications in the GLP-1 class include liraglutide and tirzepatide (a dual-pathway medication that works on both GLP-1 and GIP receptors)

consider gentle laxatives if needed Will it get better

Rare but serious riskssuch as pancreatitis, gallbladder disease, or certain thyroid tumorsmean that these medications are not suitable for everyone

[DOI] [PubMed] [Google Scholar] 27

Muscle loss from GLP-1s is not directly from the drug , but a side effect of rapid weight loss especially if youre not: Because these drugs blunt hunger so effectively , some patients eat too little overall and not enough muscle-preserving nutrients like protein