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For example, neurons co-cultured with astrocytes exhibit higher levels of glutathione compared to neurons cultured alone, demonstrating that astrocytes provide additional antioxidant defenses to neurons [104-106]

However, this circuit can become clogged, slowed down, or dysregulated, due to the sheer volume of toxins it has to deal with

doi: 10.1016/S1081-1206(10)61452-4

| Neshaminy) Xander Grasty (Soph

Nature 505 (7484), 559563

Gel pieces were de-stained and digested overnight in 10 ng/ L trypsin, as previously described (Rooney et al ., Reference Rooney, Williams, Northcote, Frankl, Price, Nisbet, Morphew and Cantacessi2022)