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Weight loss primarily depends on a combination of factors including diet, exercise, and overall lifestyle choices

If a vial is multi-dose, follow the label or pharmacist instructions for how long it can be used after opening

Abbreviations 95%CI: 95% confidence interval GLP-1: Glucagon-like peptide-1 HbA1c: Glycated hemoglobin NMA: Network meta-analysis OR: Odds ratio PICOS: Population, intervention, comparison, outcome, and study design PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses RCT: Randomized controlled trial SGLT2: Sodiumglucose cotransporter 2 SUCRA: Surface under the cumulative ranking References Avogaro A, de Kreutzenberg SV, Morieri ML, Fadini GP, Del Prato S

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doi:10.1074/jbc.M608387200

In some countries, its a significant part of the diet