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Semaglutide is generally well-tolerated with side effects that are predominantly gastrointestinal, mild-to-moderate in severity, and transient in nature, occurring most frequently during dose escalation

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Scopoletin and pinocembrin, when encapsulated in polymeric micelles, exhibit urate-lowering effects by inhibiting xanthine oxidase activity and promoting uric acid excretion, respectively, while significantly improving renal injury protection (Zeng et al., 2020