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The most common serious laboratory abnormalities (grade 3 or 4, 2%) were leukopenia, anemia, decreased phosphate, hypocalcemia, hyponatremia, increased liver enzymes, thrombocytopenia, and increased alkaline phosphatase levels (NCT03037385) [36,37]

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Immune system recalibration Immunosenescence, the gradual deterioration of immune function with age, is one of the most significant contributors to age-related disease risk

In the past we used the anti-malarial drug chloroquine for this purpose, especially for lupus with severe skin disease

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