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Membrane-binding properties of gating-modifier and pore blocking toxins: membrane interaction is not a prerequisite for modification of channel gating

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Standard collagen molecules are often too large for the body to absorb efficiently

emphasized on different drug partitioning blood cells in a dynamic in vivo system and static in vitro values, especially when repartitioning from blood cells is slower than drug clearance in plasma (Xie et al., 2015)