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Could it possibly be the B vitamins

Glucagon-like peptide-1 (GLP-1) receptor agonists represent a highly efficacious class of interventions for the treatment of type 2 diabetes, with the injectable GLP-1 analogue once-weekly semaglutide shown to be both efficacious and cost-effective versus a variety of therapies [8,9,10,11]

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Now, let's move onto #2 on the list

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Nonsteroidal Versus Steroidal Mineralocorticoid Receptor Antagonists in Heart Failure: RealWorld Evidence From a Multicenter Cohort Study