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Both L-carnitine loss into the dialysate and impaired synthesis by the kidneys contribute to a progressive carnitine deficiency in patients with end-stage renal disease (ESRD) undergoing hemodialysis (71)

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Organocatalyzed copolymerization of CO, Se and oxetane: o/se exchange reaction determining chain structure

It is used mainly as add-on to metformin when metformin alone is insufficient for glycemic control, particularly when there is a desire to minimize the risk for hypoglycemia