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The CMS-0057-F rule's operational provisions took effect January 1, 2026, with FHIR API requirements following by January 1, 2027, further pushing the ecosystem toward interoperable, point-of-care ePA exchanges ( [13] ) ( [14] )

Without adequate ATP, neurons cannot maintain their resting membrane potentials, fire action potentials efficiently, or synthesize the neurotransmitters required for memory, focus, and emotional regulation

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Tzang CC, Lin WC, Lin LH, et al

Effect of litoralon, taurine and other taurine derivatives on the heart muscle cell membrane of the locusta migratoria (migratoriodes R.F.)