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Overall, preclinical data has shown that inhibiting the proinflammatory mediators could be exploited to reduce CDLBP by reducing neuronal inflammation

Inclisiran (brand name Leqvio, manufactured by Novartis Pharmaceuticals Corporation) is a small interfering RNA (siRNA) therapy that reduces LDL cholesterol by silencing PCSK9 production in the liver

Guanfacine ER (generic Intuniv): $20 to $50 per month for generic