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To minimize side effects and maximize benefits, both medications require a gradual dose escalation

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Mitochondria are like an engine within the cells that burn fat to produce usable energy

Roberts-Wolfe, D

The primers and probes used for Mc4r and the internal control Ngf were as follows (53): -Mc4r Forward: atttgcagcctgctttcca, Reverse: tggagcgcgtaaaagatagtga FAM-MGB Probe: tgcggtggacaggta, -Ngf, Forward: tgcatagcgtaatgtccatgttg, Reverse: tctccttctgggacattgctatc, VIC-TAMRA Probe: acggttctgcctgtacgccgatca (all primers and probes were synthesized by Thermo Fisher Scientific Inc.)

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