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August 2025: Recent studies offer additional data that taking Zepbound increases someones chances of developing NAION (nonarteritic anterior ischemic optic neuropathy), a condition that causes permanent vision loss and blindness

J Clin Invest 123(9):36783684 Herranz D, Ambesi-Impiombato A, Sudderth J et al (2015) Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia

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The mechanism of GLP-1s anti-inflammatory action is still being studied, however its action has been demonstrated to involve regulating lymphocyte proliferation, maintaining regulatory peripheral T cells

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The table below compares common dosing schedules used in published research and their associated considerations