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Li J, Jia B, Cheng Y, Song Y, Li Q, Luo C

Often, the answer is yes, but understanding the underlying reasons can help mitigate this risk

Notably, after receiving LG, most patients showed improvements in steatosis and hepatocyte ballooning

This suggests that within the hypoxic microenvironment, the central regulatory factor HIF-1 is orchestrated by numerous signaling pathways apart from the oxygen sensor pathway PHDs/HIF-1/pVHL, encompassing MAPK, PI3K/AKT/mTOR, and JAK/STAT among others ( Figure 2B )