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Human apolipoprotein A-I induces cyclooxygenase-2 expression and prostaglandin I-2 release in endothelial cells through ATP-binding cassette transporter A1

Still, there is a well-documented association between higher weight and various poor health outcomes, such as a higher risk of getting CVD and diabetes in the first place

Nat Commun 12 , 4792 (2021)