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Importantly, aspiration events were identified using ICD codes in some studies, while other studies did not clearly define the method of identifying aspiration, introducing variability in outcome assessment

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Itaconate and 2,3-dicarboxypropylation Itaconate is one of the most abundant intermediates of the Krebs cycle in classically activated macrophages, resulting from citrate accumulation and up-regulation of cis -aconitate decarboxylase (CAD) ( 24 )