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First, it acts as a glutathione-sparing agent by immediately attacking free radicals
doi: 10.4110/in.2014.14.6.277 91 KimH
However, specific GLP1R and GIPR variants may correlate with differential weight loss outcomes in observational cohorts
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In mice suffering from non - alcoholic fatty liver disease (NAFLD), liraglutide significantly elevated the abundance of Akkermansia , Romboutsia , and specific members of Bacteroidales, while reducing that of Klebsiella , Anaerotruncus , Bacteroides , and several taxa within the Lachnospiraceae and Ruminococcaceae families ( Firmicutes (e.g., Lachnospiraceae , Clostridiales ) and increased beneficial taxa like Verrucomicrobia and Oscillospiraceae (Madsen et al., 2019)
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