A variety of nanocarriers have been investigated for ocular drug administration, particularly nanoparticles composed of polymers, including liposomes, dendrimers, chitosan nanoparticles, poly lactic-co-glycolic acid (PLGA) nanoparticles, and gelatin nanoparticles [365]
Rosa AR, Singh N, Whitaker E, de Brito M, Lewis AM, Vieta E et al
Toxicology 54(3):323333 Cao Y, Chen A, Jones RL, Radcliffe J, Dietrich KN, Caldwell KL, Peddada S, Rogan WJ (2011) Efficacy of succimer chelation of mercury at background exposures in toddlers: a randomized trial
10.1016/j.semcancer.2019.07.003 192 MussaiF.De SantoC.Abu-DayyehI.BoothS.QuekL.Mcewen-SmithR
Another critical consideration is the substantial pharmacokinetic limitations of curcumin, which are one of the core bottlenecks hindering its clinical translation
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