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Infiltration of M1-type macrophages into visceral fat leads to chronic release of pro-inflammatory cytokines, such as IL-1, which drive ovarian interstitial fibrosis and hemodynamic changes (62, 63)

Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors

The GIP receptor is highly expressed in adipose tissue, and acute infusion of GIP under conditions of high insulin and modest hyperglycemia increases adipose tissue glucose uptake, blood flow, and triglyceride hydrolysis in humans [20, 21, 22]

001 ) in respect to the control group [Table 2]

Encouraging the growth of beneficial gut microbiota , crucial for digestion and overall health