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The complementary mechanisms are believed to provide synergistic healing benefits

308,362,363,372,434,435,436 Additionally, EULAR guidelines recommend losartan for patients with hypertension and fenofibrate for those with hyperlipidemia, both of which have mild uricosuric effects

In addition, Dula decreased the oxidative stress biomarker malondialdehyde (MDA) and increased the antioxidant enzymes (total antioxidant capacity (TAC), reduced glutathione (GSH), and superoxide dismutase (SOD) concentrations)