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+ = observed, - = not observed, A = EMA product information ( Human An earlier review on pharmacotherapy for gestational diabetes reported no human data on the safety of GLP-1 agonists during pregnancy and concluded that these drugs cannot be recommended in pregnancy (30)

A: Yes, it has been shown to influence GABA and monoamine metabolism in experimental systems, particularly affecting enzymes like MAO-A

After 9-12 months, the top quartile of patients achieved a BMI reduction of at least 11.2%, while the bottom quartile had less than 1.9% BMI reduction, or even experienced weight gain

No discernible longitudinal variation was seen in the mean fT4 and TSH levels between KD initiation and the last follow-up (12 months) [99]

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