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HA functioned not only as a delivery vehicle but also as an immunomodulatory agent, binding to CD44 receptors on immune cells such as macrophages, thereby suppressing their activation through TLR2/4 pathway modulation and reducing pro-inflammatory cytokine production

died but potentially broader in scope, influencing multiple systems beyond sleep

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Targeting hands, feet, or dark knuckles The skin on hands and feet is thicker and more exposed to washing, sun, and dryness

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For instance, a derivatization method and GC for screening L-carnitine enantiomer purity were GC developed in the study by Abreht et al