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Provided the gshF gene can successfully induce the production of higher GSH levels in the target organisms cells, the increased glutathione pool can increase the cells buffering capacity for oxidative stress

Delivery method also plays a role

doi: 10.1016/j.jep.2013.11.040

Since glutathione (GSH) is the predominant antioxidant in the lungs, we proposed that changes in glutathione redox potential (E h ) would alter cell signaling and have an effect on ENaC open probability ( P o )

Without adequate glutathione, the livers ability to process and eliminate toxins is compromised