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10.1016/j.jphs.2023.10.002 184 XuC
The 1-hydroxy enzyme is also widely expressed in non-kidney cells including immune cells and is able to convert the inactive 25(OH)D into the active 1,25(OH) 2 D in either an autocrine or paracrine manner [9]
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Firstly, the permeability of EBA increased after 24-h incubation with 3-PLG-ibu, and secondly, in inflammatory condition besides the 3-PLG-ibu-A-GSH the free ibuprofen treated group also significantly strengthened the integrity of the BBB model for the bigger transcellular marker molecule (Fig
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