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Second signals rescue B cells from activation-induced mitochondrial dysfunction and death

Moreover, the normal NP is an avascular and aneural tissue, where NP cells are far at least 8 mm from the nearest blood supply [22], which makes nutrients and waste exchange based solely on diffusion and self-healing extremely difficult to achieve [23]

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NET formation is independent of gasdermin D and pyroptotic cell death

[56] [57] Coverage for obesity-only indications remains variable across private insurance plans and public payers, and Medicare coverage has historically been restricted for drugs used solely for weight loss